Coevolução de genética e sistemas de produção, um caminho para a sustentabilidade: Privilegiar a capacidade de suporte do solo e a qualidade da água superficial e profunda na sua metodologia.

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Programa cooperativo de pesquisa sobre pulgões de trigo nos países do cone sul da América.

bitstream/item/116625/1/FOL-00104.pdfTrabalho apresentado na IX Reunião Anual Conjunta de Pesquisa de Trigo, lONDRINA, 1977

The co-evolution of societal issues, technologies and industry regimes: three case studies of the American automobile industry

This thesis contributes to closing a gap in the field of science, technology and innovation (STI) policy research: despite many theoretical advances in the field, we still do not know why some urgent societal issues (or ‘challenges’) remain unaddressed, notwithstanding the technological advances that could potentially address them. In particular, radical technological innovations – innovations that depart from the established technological trajectory – would offer greatest potential to address societal challenges. While the source of radical innovations is often new entrepreneurial firms, established firms (‘incumbents’) are likely to play an important role in developing them because of the vast resources and complementary assets they possess. Incumbents however, face few immediate incentives to develop radical innovations in response to societal challenges. The analytical puzzle of this thesis is thus to explain how, when, and why industries change (or not) their strategies (in particular, their technological strategy) in order to address a societal problem. This puzzle is disentangled into interrelated research questions: A) How do societal issue­‐related pressures (on the incumbent industry) from different domains (namely, civil society, science, political arena, economy) evolve? B) How does the incumbent industry respond to changing pressures around societal issues, in terms of technological, political, cultural and economic strategies? C) In particular, when and why do industry actors decide to develop substantive technological responses? To answer these questions, the thesis develops a new analytical perspective that combines insights from (a) issue life­‐cycle and issue attention cycle theories (from the Business & Society field) with (b) the so­‐called ‘Triple Embeddedness Framework’ and (c) concepts from business strategies, innovation management, corporate political strategies, and technology policy. This novel perspective represents an ideal­‐typical model of issue evolution (‘issue life ­‐cycle’). The model, which I call the Dialectic Issue Life­‐Cycle (DILC) model, is applied to three case studies of the American automobile industry’s responses to various societal problems (local air pollution, auto and highway safety, and climate change). Combining qualitative and quantitative research methods in an original way, the case studies aim not only to investigate the validity of the framework, which also provides conceptual answers to the research questions, but also to further refine it and nuance the conceptual answers. By explaining how incumbent industry actors respond to societal challenges, this thesis ultimately contributes to the practical policy debate of how incumbents can be stimulated to develop radical innovations that help address societal challenges

Confined Placental Mosaicism in Chorionic Vilus Sampling - Case Report

Objectives: Chorionic Vilus Sampling (CVS) has several advantages over amniocentesis: it may be performed at an earlier gestational age, the results are quicker to obtain and there’s a lower miscarriage risk – 1%. However, the higher prevalence of discrepant fetal and vilus sampling material’s karyotype findings is a disadvantage of this technique – 0.5%. This is caused, amongst other causes, by placental mosaicism which consists of two genetically different cell lines. There are three types of placental mosaicism according to the abnormal cell line location: Type I – in the cytotrophoblast; Type II – in the vilus’ stroma; Type III – in both the above locations. Material and Methods: We present a case report about a 36-year-old pregnant woman going through our Department’s 1st trimester combined screening program; a CVS was performed, which showed Confined Placental Mosaicism (CPM). Results and Conclusion: Although the pregnant woman was in the low-risk group for aneuploidy, the patient wanted the cytogenetic study to be performed in order to reduce maternal anxiety. CVS was performed at the gestational age of 12 weeks + 5 days and the karyotype was 47XY+2/46XY. For the correct interpretation of this data an amniocentesis was performed at the gestational age of 15 weeks + 6 days, which showed a 46XY karyotype. We therefore conclude that the cytogenetic analysis of the CVS was the result of a CPM. A careful follow-up including fetal echocardiogram and seriated ultrasonographic monitoring was used to safely exclude malformations and fetal growth restriction. We verified no occurences throughout pregnancy, delivery and perinatal period. CVS practice was recently implemented in our country and has many advantages over amniocentesis. Besides the fact that an earlier gestational age usually means less affective bonding to the fetus and therefore makes medical termination of pregnancy somewhat less difficult, one should consider specific situations like the one reported in which CPM may be diagnosed. This condition is associated with increased risk of fetal growth restriction, so the clinician should be aware of the need for a more careful follow-up, since perinatal complications, which should be anticipated and treated, can be expected in 16-21% of these cases

Características das cultivares de trigo recomendadas para cultivo em áreas aptas ao arroz irrigado do Rio Grande do Sul.

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